IMMUNE CELL DYNAMICS
Welcome to the ÖNFELT LAB
In our latest work published in Nature Communications we investigate the modulation of lytic molecules in γδ T cells and show how it restrains their serial killing capability of tumor cells.
In particular, the limited co-occurrence of granzyme B and perforin seems to play a critical role and can be of importance for the development of new adoptive immunotherapies.
In the example video, the colocalization of granzyme B and perforin is shown inside a γδ T cell.
Read more about it in Nature Communications.
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KTH, SciLifeLab
Önfelt Lab, Biophysics, Gamma 3
Tomtebodavägen 23A
SE-171 65 Solna
Sweden